The 2014 Innate Immunity Summit

London, London
Monday, 10 November 2014

This event will be held at The O2,  a large entertainment district on the Greenwich peninsula in South East London, England.
The 2014 Innate Immunity Summit
Monday, 10 November 2014 09:30 -
Wednesday, 12 November 2014 17:00

Cineworld: The O2
Peninsula Square
SE10 0DX
United Kingdom

Map and Directions

A three day event discussing aspects of the innate immune system. 

This year there are three main topics for discussion

  • The Innate Immunity Interactions with Pathogens 
  • Interactions of the Innate and Adaptive Immune Systems
  • Therapeutic applications of the Innate Immune system

With plenty of opportunity  for networking and debate, this informal international  meeting will bring you up to date with current research and thinking regarding an organisms first line of defense.

Who Should Attend: Academic and biotechnology/biopharma research professionals interested in function and potency of immune response components against pathogens and tumours; also scientists interested in how understa nding these mechanisms can inform the design of biological therapeutics and their mechanisms of action , with translational implications for therapy.

This event has an open poster session.  Posters can be submitted on any subject related to Innate Immunity

This event has CPD accreditation.

The deadline for abstract submissions for oral presentation is July 10th 2014. Abstracts for poster presentation only can be submitted up to two weeks before the event. You can download the instructions for authors at:

Program Outline

Day 1:  Innate Immunity Interactions with Pathogens
Infectious disease are still a major cause of morbidity and mortality worldwide. Innate immunity is of paramount importance for the control of pathogens in the early stages of the infection and for the engenderment and expansion of acquired immunity. This will be a premier forum for the presentation of cutting-edge research on how the interaction between innate immune mechanisms and pathogens impacts on host resistance, immunoevasion, immunodeficiencies and vaccine efficacy, providing 

 a deep insight into future research and more rational measures to prevent and treat infectious diseases of humans and animals.  Session Chair:  Dr Pietro Mastroeni, Cambridge University, UK

Day 2:  Investigating interactions of the Innate and Adaptive Immune Systems
The cells of the innate immune system play a crucial part in immune defense against disease but also respond to the presence of malignant cells, initiating and subsequently directing adaptive immune responses. The session will discuss the roles of different components of the innate immune system, with focus on disease mechanisms and interactions between inflammatory cells, antibodies and pathogenic or tumour antigens and how these impact on disease progression. The session will draw on new cutting edge research and will provide ample opportunity for networking and informal discussions.
Session Chair:  Dr Sophia N. Karagiannis, Senior Lecturer in Translational Cancer Immunology, Head of Cancer Antibody Discovery and Immunotherapy, St John’s Institute of Dermatology, Division of Genetics and Molecular Medicine, King’s College London School of Medicine, UK

Day 3:  Therapeutic applications of the Innate Immune system
The identification of antigen recognition receptors for innate immunity has sparked great interest in therapeutic manipulation of the innate immune system. For example Toll-like receptor agonists are being developed for the treatment of cancer, allergies and viral infections, and as adjuvants for cancer and disease vaccines.  This session will explore current research and applications of the innate system for therapeutic applications. There will be plenty of opportunity for discussion and debate and we encourage submission of abstracts for both oral and poster presentation. Session Chair:  To be confirmed

Talks Include:
Exploring pathogen recognition in innate immunity using Drosophila as a model host
Dr Petros Ligoxygakis, Associate Professor of Genetics, University of Oxford, UK

Non-specific Stressors: Under-appreciated Innate Defenses
Dr Edmund LeGrand
, Adjunct professor , Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine,  University of Tennessee, Knoxville, TN, USA

Understanding the roles of innate and  adaptive immunity in the mechanisms of action of immunomodulatory antibodies.
Dr  Stephen A Beers,  Antibody and Vaccine Group, Faculty of Medicine, University of Southampton, UK

HPV and innate immunity
Dr Uzma Hasan
, Oncoviruses and Innate Immunity Centre International de Recherche en Infectiologie, University Lyon, Hopital Lyon Sud, France

TRIF-mediated TLR3 and TLR4 signaling is negatively regulated by ADAM15
Dr Sinead Miggin, Lecturer and Principal Investigator, National University of Ireland Maynooth, Ireland

Purinergic signalling in controlling of intracellular parasites
Dr Robson Coutinho-Silva, Immunobiology Program, Biophysics Institute Carlos Chagas Filho, Federal University of Rio de Janeiro

Soluble pattern recognition molecules and associated proteins – update on the lectin pathway of the complement system
Professor Steffen Thiel, Department of Biomedicine, Aarhus University, Denmark

Reg3 proteins in the mammalian intestine.
Professor Jerry Wells, Host-Microbe Interactomics - Wageningen, The Netherlands 

Interaction of HIV with plasmacytoid dendritic cells and its relevance for HIV pathogenesis
Dr Adriano Boasso, Principal Investigator - Research Fellow, Imperial College London, UK

Lipid rafts influence NLR mediated immune responses against bacterial infections
Dr Sanjay Batra, Assistant Professor, Louisiana State University, USA

Novel Interactions between Fas and TLR signalling
Dr Elizabeth Brint, Lecturer and Principal Investigator,University College Cork, Ireland

Paramyxovirus Inhibition of Human Complement  Pathways
Professor Griffith Parks, Dept. of Microbiology and Immunology, Wake Forest School of Medicine, USA

B- cells at the interface between innate and acquired immunity to bacterial pathogens

Dr Pietro Mastroeni, Reader in Infection and Immunity, University of Cambridge, UK

The MHC class II-associated invariant chain controls innate and adaptive immunity in B cells
Dr Bénédicte Manoury,  PI, DR2, CNRS,  Hôpital Necker; Unité INSERM U1151, Paris, France

Sepsis as a Model of Impaired Communication between the Innate and Adaptive Immune Systems
Dr Jim Faix, Director of Chemistry & Immunology, Director of Point-of-Care Testing, Department of Pathology, Stanford University Medical Center, Stanford, USA


B cells and tumours: novel insights into tumour-induced immune escape
Dr Sophia N. Karagiannis, Senior Lecturer in Translational Cancer Immunology, Head of Cancer Antibody Discovery and Immunotherapy, St John’s Institute of Dermatology, Division of Genetics and Molecular Medicine, King’s College London School of Medicine, UK

Platelets as immune cells
Dr Fabrice Cognasse,  Senior Scientist, Deputy Director for Scientific Affairs, the Auvergne-Loire Regional Branch of the French National Blood System EFS,  Etablissement Français du Sang Auvergne-Loire, France

Intranasal vasoactive intestinal polypeptide (VIP) safely corrects multiple abnormalities in proteomics of innate immune responses and simultaneously restores regulation to differential genomic activation and suppression
Dr Ritchie C. Shoemaker, Center for Research on Biotoxin Associated Illnesses, USA

Regulation of autoimmune myocarditis andinflammatory cardiomyopathy by innate immunity
Dr Przemyslaw Blyszczuk, Junior Group Leader, Cardioimmunology, University of Zurich, Switzerland

High-intensity ultra-short electric pulse applications in modulating innate immunity
Dr Sunil K. Joshi, Assistant Professor, School of Molecular Diagnostics & Translational Sciences, College of Health Sciences and Frank Reidy Research Center of Bioelectrics, Old Dominion University, Norfolk, VA, USA

Therapeutic Role of Probiotics in Inflammatory Joint Diseases

Dr Vinod Singh, Associate Professor and Head,  Department of Microbiology,Barkatullah University, Bhopal-462026(M.P), India

M1/M2 Macrophages: A Copernican Revelation in Immunology
Dr Charles Mills, BioMedical Consultants, United States

Inflammatory networks controlling cancer metastatic dissemination
Dr Victoria Sanz-Moreno, PhD, Cancer Research UK Career Development Fellow, Head of the Tumour Plasticity lab, Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College, London SE11UL, United Kingdom

Obesity and the skeleton 
Professor Juliet Compston, University of Cambridge, UK

Speakers Include:
Dr Sema Becerik, Ege University, Turkey
Dr Claudia Monaco, Imperial College London, United Kingdom


Contact Details

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